Sacral nerve stimulation with appropriate parameters improves constipation in rats by enhancing colon motility mediated via the autonomic-cholinergic mechanisms
نویسندگان
چکیده
منابع مشابه
Sacral nerve stimulation for intractable constipation.
OBJECTIVE Traditional surgical procedures for intractable idiopathic constipation are associated with a variable outcome and substantial morbidity. The symptomatic response, physiological effect and effect on quality of life of sacral nerve stimulation (SNS) were evaluated in patients with constipation (slow transit and normal transit with impaired evacuation). METHODS In a prospective study ...
متن کاملRandomized clinical trial of sacral nerve stimulation for refractory constipation.
BACKGROUND Open studies have reported favourable results for sacral nerve stimulation in the treatment of refractory constipation. Here, its efficacy was assessed in a double-blind crossover RCT. METHODS Patients with at least two of the following criteria were included: fewer than three bowel movements per week; straining to evacuate on more than 25 per cent of attempts; or sensation of inco...
متن کاملSacral Nerve Stimulation Through the Sacral Hiatus
Sacral nerve stimulation through the retrograde approach has been used for peroneal or irritable bowel syndrome through the retrograde approach. However, several reasons, lead could not be advanced down ward. In this case, anterograde sacral nerve stimulation through the sacral hiatus could be used. The aim of this report is to present of technique of sacral nerve root stimulation through the s...
متن کاملEffects of sacral nerve stimulation with acupuncture on gut transit time and c-kit expression in colon of rats with slow transit constipation.
Sacral nerve stimulation (SNS) is an alternative surgical approach to alleviate fecal incontinence and constipation. This study aimed to explore the effects and underlying mechanisms of SNS with acupuncture on gut transit time and colon c-kit protein expression in rats with slow transit constipation (STC). Fifty Sprague-Dawley rats were randomly divided into five groups: blank control, SNS, Mos...
متن کاملSacral Malformations - Implications in Sacral Nerve Stimulation
One of the most important steps of this technique is the correct topographic anatomic identification of the posterior sacral foramina on the body surface of the sacrum [6,7]. Although the sacrum’s anatomy is recognized to be highly variable. In the literature there are several studies regarding the variable morphology of the sacrum that also shows high incidence of sacral malformations, ranging...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Gastrointestinal and Liver Physiology
سال: 2019
ISSN: 0193-1857,1522-1547
DOI: 10.1152/ajpgi.00150.2018